diff --git a/devel/py-nodeenv/Makefile b/devel/py-nodeenv/Makefile
index 45aa09c43024..f334dfb1336c 100644
--- a/devel/py-nodeenv/Makefile
+++ b/devel/py-nodeenv/Makefile
@@ -11,6 +11,8 @@ WWW=		https://ekalinin.github.io/nodeenv/
 LICENSE=	BSD3CLAUSE
 LICENSE_FILE=	${WRKSRC}/LICENSE
 
+RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}setuptools>=0:devel/py-setuptools@${PY_FLAVOR}
+
 USES=		python
 USE_PYTHON=	autoplist distutils