diff --git a/textproc/py-markdown2/Makefile b/textproc/py-markdown2/Makefile
index 91e3bfb40244..0d18d503fe60 100644
--- a/textproc/py-markdown2/Makefile
+++ b/textproc/py-markdown2/Makefile
@@ -1,6 +1,5 @@
 PORTNAME=	markdown2
-PORTVERSION=	2.4.13
-PORTREVISION=	1
+PORTVERSION=	2.5.4
 CATEGORIES=	textproc python
 MASTER_SITES=	PYPI
 PKGNAMEPREFIX=	${PYTHON_PKGNAMEPREFIX}
@@ -12,19 +11,24 @@ WWW=		https://github.com/trentm/python-markdown2
 LICENSE=	MIT
 LICENSE_FILE=	${WRKSRC}/LICENSE.txt
 
+BUILD_DEPENDS=	${PYTHON_PKGNAMEPREFIX}setuptools>=0:devel/py-setuptools@${PY_FLAVOR} \
+		${PYTHON_PKGNAMEPREFIX}wheel>=0:devel/py-wheel@${PY_FLAVOR}
+
 USES=		python
-USE_PYTHON=	autoplist concurrent distutils
+USE_PYTHON=	autoplist concurrent pep517
 
 TEST_ENV=	PYTHONPATH=${STAGEDIR}${PYTHONPREFIX_SITELIBDIR}
 
 NO_ARCH=	yes
 
-OPTIONS_DEFINE=		SYNTAX WAVEDROM
-OPTIONS_DEFAULT=	SYNTAX WAVEDROM
+OPTIONS_DEFINE=		LATEX SYNTAX WAVEDROM
+OPTIONS_DEFAULT=	LATEX SYNTAX WAVEDROM
 
+LATEX_DESC=		LaTeX to MathML conversion support
 SYNTAX_DESC=		Code syntax highlighting support
 WAVEDROM_DESC=		WaveDrom support
 
+LATEX_RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}latex2mathml>=0:textproc/py-latex2mathml@${PY_FLAVOR}
 SYNTAX_RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}pygments>=2.7.3:textproc/py-pygments@${PY_FLAVOR}
 WAVEDROM_RUN_DEPENDS=	${PYTHON_PKGNAMEPREFIX}wavedrom>0:textproc/py-wavedrom@${PY_FLAVOR}
 
diff --git a/textproc/py-markdown2/distinfo b/textproc/py-markdown2/distinfo
index cc629e5fd7c9..637c8f0438ab 100644
--- a/textproc/py-markdown2/distinfo
+++ b/textproc/py-markdown2/distinfo
@@ -1,3 +1,3 @@
-TIMESTAMP = 1709553350
-SHA256 (markdown2-2.4.13.tar.gz) = 18ceb56590da77f2c22382e55be48c15b3c8f0c71d6398def387275e6c347a9f
-SIZE (markdown2-2.4.13.tar.gz) = 130464
+TIMESTAMP = 1762538640
+SHA256 (markdown2-2.5.4.tar.gz) = a09873f0b3c23dbfae589b0080587df52ad75bb09a5fa6559147554736676889
+SIZE (markdown2-2.5.4.tar.gz) = 145652